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Who Is at Highest Risk for Suffering Complications from Hib?

Who Is at Highest Risk for Suffering Complications from Hib?

Asplenic patients (people without a spleen or who have dysfunctional spleens such as individuals with sickle cell anemia or celiac disease) are predisposed to the development of serious infections from Haemophilus influenzae, Neisseria meningitides, and Streptococcus pneumoniae.1 Persons with underlying medical conditions such as HIV infection, alcoholism, cancer, pulmonary disease, and women who are pregnant may also be at greater risk of infection that may to lead to complications.2  In the case of bacterial meningitis, including H. influenzae meningitis, developing complications or dying is related to age, underlying health of the patient, severity of the disease, and timing of antibiotic therapy.3

IMPORTANT NOTE: NVIC encourages you to become fully informed about Haemophilus Influenzae Type B (Hib) and the Hib vaccine by reading all sections in the Table of Contents, which contain many links and resources such as the manufacturer product information inserts, and to speak with one or more trusted health care professionals before making a vaccination decision for yourself or your child. This information is for educational purposes only and is not intended as medical advice.

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1 Bridgen ML Detection, Education and Management of the Asplenic or Hyposplenic Patient Am Fam Physician. 2001 Feb 1;63(3):499-508.

2 Buensalido JAL Haemophilus Influenzae Infections Clinical Presentation Medscape Sep. 7, 2018

3 Kaplan SL. Neurologic Complications of Bacterial Meningitis in Children. Wolters Kluwer. Nov. 3, 2017

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