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Can Mumps Cause Injury and Death?

disease injury and death

Complications and death from mumps infections are rare.1 Complications include inflammation of the testicles in males, which can, in rare cases, result in atrophied testicles and lead to sterility.2

Aseptic meningitis may also develop as a complication of mumps.3 Rarely, mumps may also cause pancreatitis,4 encephalitis,5 6 oophoritis,7 hearing loss,8 9 mastitis,10 11 myocarditis,12 13 thyroiditis,14 nephritis,15 16 arthritis,17 18 diabetes,19 and thrombocytopenic purpura.20 Spontaneous abortions (miscarriage) in pregnant women infected with mumps have also been reported21.

No mumps related deaths have been reported in recent years.22

IMPORTANT NOTE: NVIC encourages you to become fully informed about Mumps and the Mumps vaccine by reading all sections in the Table of Contents, which contain many links and resources such as the manufacturer product information inserts, and to speak with one or more trusted health care professionals before making a vaccination decision for yourself or your child. This information is for educational purposes only and is not intended as medical advice.

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1 Mayo Clinic. Mumps – Overview. Aug. 12, 2015

2 CDC. Mumps - Complications Epidemiology and Prevention of Vaccine-Preventable Diseases (The Pink Book). 13th ed. 2015.

3 Ibid

4 Vanlioglu B, Chua TC. Presentation of mumps infection as acute pancreatitis without parotitis. Pancreas. 2011 Jan;40(1):167-8

5 Johnstone JA, Ross CAC, Dunn M. Meningitis and Encephalitis Associated with Mumps Infection- A 10-Year Survey. Arch Dis Child. 1972 Aug; 47(254): 647–651.

6 Atkinson RE, Kent S, Fidler K. Mumps encephalitis with brainstem involvement: significant morbidity and diagnostic dilemmas Arch Dis Child. 2011;96:A54-A55.

7 Morrison JC, Givens JR, et al. Mumps oophoritis: a cause of premature menopause. Fertil Steril. 1975 Jul;26(7):655-9.

8 Mizushima N, Murakami Y. Deafness following mumps: the possible pathogenesis and incidence of deafness. Auris Nasus Larynx. 1986;13 Suppl 1:S55-7.

9 Kayan A, Bellman H. Bilateral sensorineural hearing loss due to mumps. Br J Clin Pract. 1990 Dec;44(12):757-9.

10 LEE CM. Primary virus mastitis from mumps. Va Med Mon (1918). 1946 Jul;73:327.

11  Happel JS. Mastitis in the male--a rare complication of mumps. Br Med J. 1965 Oct 30; 2(5469): 1041.

12 Hussain S, Zahid MF, MUMPS MYOCARDITIS: A FORGOTTEN DISEASE? J Ayub Med Coll Abbottabad. 2016 Jan-Mar;28(1):201-3.

13 Arita M, Ueno Y, Masuyama Y, Complete heart block in mumps myocarditis. Br Heart J. 1981 Sep; 46(3): 342–344.

14 Parmar RC, Bavdekar SB, Thyroiditis as a presenting feature of mumps. Pediatr Infect Dis J. 2001 Jun;20(6):637-8.

15 Helin I, Carstensen H. Nephrotic syndrome after mumps virus infection. Am J Dis Child. 1983 Nov;137(11):1126.

16 Lin CY, Chen WP, Chiang H. Mumps associated with nephritis. Child Nephrol Urol. 1990;10(2):68-71.

17 Gordon SC, Lauter CB. Mumps arthritis: a review of the literature. Rev Infect Dis. 1984 May-Jun;6(3):338-44.

18 Bayer AS. Arthritis associated with common viral infections: mumps, coxsackievirus, and adenovirus. Postgrad Med. 1980 Jul;68(1):55-8, 60, 63-4.

19 Reddy CM, Crump EP. Diabetes mellitus following mumps. J Natl Med Assoc. 1976 Nov; 68(6): 459–460.

20Graham DY, Brown CH III, et al. Thrombocytopenia. A complication of mumps. JAMA. 1974 Mar 11;227(10):1162-4.

21 CDC. Mumps for Healthcare Providers – Mumps during Pregnancy. Feb. 16, 2018

22 CDC. Mumps - Complications Epidemiology and Prevention of Vaccine-Preventable Diseases (The Pink Book). 13th ed. 2015.

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