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Who is at Highest Risk for Suffering from Rotavirus Complications?


Severe dehydration and diarrhea from rotavirus can cause metabolic acidosis and electrolyte imbalances in infants and young children. There is no reliable way to predict who will suffer these serious complications.

Immunocompromised children such as those who have received solid organ or bone marrow transplants, or who suffer from congenital immunodeficiency may be at higher risk for complications. These complications may include severe gastrointestinal illness that persists, and these children may have abnormal findings in several organ systems, including the liver and kidney.1

IMPORTANT NOTE: NVIC encourages you to become fully informed about rotavirus and rotavirus vaccines by reading all sections in the Table of Contents, which contain many links and resources such as the manufacturer product information inserts, and to speak with one or more trusted health care professionals before making a vaccination decision for yourself or your child. This information is for educational purposes only and is not intended as medical advice.

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1 Communication and Education Branch, National Center for Immunization and Respiratory Diseases (NCIRD) and the Centers for Disease Control (CDC). Rotavirus  In: Epidemiology and Prevention of Vaccine-Preventable Diseases. 13th ed. Centers for Disease Control (CDC) 2015; Pg. 312. Updated November 2020. Accessed Apr. 4, 2021.

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