Who is at highest risk for complications from Ebola vaccine?

In clinical trials of ERVEBO Ebola Virus Vaccine, arthritis was found to occur in up to 24 percent of vaccine trial participants. Arthritis events included osteoarthritis, monoarthritis, polyarthritis, joint effusion, and joint swelling. One study conducted in Switzerland reported that 24 percent of participants developed arthritic conditions, with some people having symptoms that persisted long-term or recurred. 

Persons with a past history of arthritis and females were found to be at a higher risk of arthritis post-vaccination. 

Women who are inadvertently vaccinated during pregnancy or who become pregnant within two months of vaccination may be at higher risk of miscarriage. Eighty-four women were unintentionally vaccinated in early pregnancy or within two months of vaccination or enrollment in the clinical trial. Forty-five percent (14 of 31) of pregnant women who were immediately vaccinated experienced a miscarriage in comparison to 33 percent (11 of 33) of unvaccinated women. 

---